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The most common screening tests for lead poisoning are reviewed. Stippled red cells are inconstant and appear too late. Blood lead concentrations are difficult to measure accurately and often are uncorrelated with body lead stores. Excess of delta aminolevulinic acid and coproporphyrin in urine does not appear early enough. A marked increase of erythrocyte protoporphyrin level practically clinches the diagnosis, later confirmed by increase of lead in urine after an EDTA lead-mobilization test. Measurements of erythrocyte protoporphyrin levels are easy to perform, more sensitive, more precocious and cheaper than the other methods, but their relative lack of specificity must be borne in mind.
Y Nordmann, and
J F Devars du Mayne
December 1982,
La Nouvelle presse medicale,
Y Nordmann, and
J F Devars du Mayne
September 1981,
American journal of veterinary research,
Y Nordmann, and
J F Devars du Mayne
March 1982,
Annals of clinical biochemistry,
Y Nordmann, and
J F Devars du Mayne
November 1982,
Canadian Medical Association journal,
Y Nordmann, and
J F Devars du Mayne
August 1983,
Clinical chemistry,
Y Nordmann, and
J F Devars du Mayne
August 1973,
Biochemical medicine,
Y Nordmann, and
J F Devars du Mayne
January 1952,
Archives des maladies professionnelles de medecine du travail et de securite sociale,
Y Nordmann, and
J F Devars du Mayne
January 1984,
International archives of occupational and environmental health,
Y Nordmann, and
J F Devars du Mayne
January 1992,
The New England journal of medicine,
Y Nordmann, and
J F Devars du Mayne
February 1981,
Veterinary and human toxicology,
