Klinefelter syndrome: predisposition to acute non-lymphocytic leukaemia? 1980

J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander

UI MeSH Term Description Entries
D007713 Klinefelter Syndrome A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.). 48,XXYY Syndrome,49,XXXXY Syndrome,Klinefelter Syndrome, Variants,Klinefelter's Syndrome,XXXY Males,XXY Syndrome,XXY Trisomy,Xxyy Syndrome,Klinefelter Syndromes,Klinefelter Syndromes, Variants,Klinefelters Syndrome,Syndrome, Klinefelter,Syndrome, Klinefelter's,Syndrome, Variants Klinefelter,Syndrome, XXY,Syndrome, Xxyy,Syndromes, Klinefelter,Syndromes, Variants Klinefelter,Syndromes, XXY,Syndromes, Xxyy,Trisomies, XXY,Trisomy, XXY,XXXY Male,XXY Syndromes,XXY Trisomies,Xxyy Syndromes
D007938 Leukemia A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) Leucocythaemia,Leucocythemia,Leucocythaemias,Leucocythemias,Leukemias
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D004198 Disease Susceptibility A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases. Diathesis,Susceptibility, Disease,Diatheses,Disease Susceptibilities,Susceptibilities, Disease
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000208 Acute Disease Disease having a short and relatively severe course. Acute Diseases,Disease, Acute,Diseases, Acute
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
May 1980, Lancet (London, England),
J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
June 2009, Presse medicale (Paris, France : 1983),
J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
February 1980, Clinics in haematology,
J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
August 1985, Scandinavian journal of haematology,
J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
June 2010, Collegium antropologicum,
J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
July 1987, The Journal of the Association of Physicians of India,
J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
May 1974, Irish journal of medical science,
J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
December 1982, Australian and New Zealand journal of medicine,
J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
January 1984, The American journal of pediatric hematology/oncology,
J P Geraedts, and A Mol, and E Briët, and C A Hartgrink-Groeneveld, and G J den Ottolander
August 1988, The Journal of the Association of Physicians of India,
Copied contents to your clipboard!