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To elucidate the role of prolactin in the control of pituitary-ovarian function, eight healthy women were given 80 mg of synthetic thyrotropin-releasing hormone (TRH) orally on two consecutive days during the luteal phase of their menstrual cycle. TRH elevated serum prolactin to a mean concentration of 43.8 ng/ml on the first day and to 15.5 ng/ml on the second day. The reduced response to the second TRH dose was statistically significant (p < 0.05). Accompanying changes in concentrations of gonadotropins or ovarian steroids were not consistent. Short-term oral administration of TRH and/or the temporary hyperprolactinemia induced by its use do not modify the pituitary-ovarian function during the luteal phase of the menstrual cycle.
O Ylikorkala, and
M Y Dawood, and
S Kivinen
January 1986,
Gynakologische Rundschau,
O Ylikorkala, and
M Y Dawood, and
S Kivinen
March 1987,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
O Ylikorkala, and
M Y Dawood, and
S Kivinen
October 1987,
Medicina clinica,
O Ylikorkala, and
M Y Dawood, and
S Kivinen
June 1979,
Fertility and sterility,
O Ylikorkala, and
M Y Dawood, and
S Kivinen
July 1979,
Archives of gynecology,
O Ylikorkala, and
M Y Dawood, and
S Kivinen
November 1979,
Fertility and sterility,
O Ylikorkala, and
M Y Dawood, and
S Kivinen
January 1978,
Hormone research,
O Ylikorkala, and
M Y Dawood, and
S Kivinen
January 1985,
Andrologia,
O Ylikorkala, and
M Y Dawood, and
S Kivinen
May 1982,
The Journal of clinical endocrinology and metabolism,
O Ylikorkala, and
M Y Dawood, and
S Kivinen
March 1979,
Journal of neurosurgery,
