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The urethral closure pressure profile (UPP) examination was performed routinely together with the administration of alpha-blockers. By the measurement of UPP, we can understand whether the organic changes at the bladder neck have already occurred or not. Further, by calculating the decreasing rate of the pressure at the bladder neck (BNP) and the maximum urethral closure pressure (MP), we can determine which nerve component is affected. Particularly, when we want to detect the affected nerve component in a mild disorder of vesico-urethral function, the measurement of UPP is quite useful as one of the screening urodynamic tests.
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