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Six hundred erythrocyte-plasma lithium ratios have been gathered from 67 patients presenting affective disorders. Ratios values in relapse period are not altered regarding those in remission phase as between periods with neuroleptic associations and those without. Ratios values are not noticeably modified by personality, sex and the evolution of affective disorders. But lithium preventive action is essentially found in patients with high erythrocyte-plasma.
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