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Lymphocyte transformation, production of neutralising antibody, and the development of antirabies IgG antibody were studied in ten healthy volunteers in response to 0.8 ml of human diploid-cell strain (HDCS) rabies vaccine administered on one occasion in divided doses in 8 intradermal (i.d.) sites. All ten volunteers rapidly developed substantial titres of rabies antibody, and eight of the ten had T lymphocytes that were immunologically stimulated by HDCS rabies-virus antigen. Postexposure treatment with 0.8 ml of HDCS vaccine given at 4 i.d. sites completely protected fourteen rabbits from death by street virus. The results suggest that in developing countries patients could be protected with small volumes of potent tissue-culture vaccine administered intradermally shortly after exposure.
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
January 1978,
Developments in biological standardization,
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
October 1989,
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire,
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
August 1980,
The Journal of infectious diseases,
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
December 1976,
JAMA,
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
January 2000,
Wilderness & environmental medicine,
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
January 1971,
Bulletin of the World Health Organization,
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
May 1984,
American journal of public health,
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
July 1978,
Journal of biological standardization,
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
December 1986,
The Southeast Asian journal of tropical medicine and public health,
K G Nicholson, and
H Prestage, and
P J Cole, and
G S Turner, and
S P Bauer
February 1990,
Casopis lekaru ceskych,
