Biomaterial Database

[Acrodermatitis enteropathica; zinc sulfate therapy]. 1977

M Larregue, and J J Baudon, and J L Fontaine, and G Feldmann, and R Laplane

We present the case of two siblings with acrodermatitis enteropathica. Zinc levels were low. Oral administration of 100 mg of zinc sulfate allowed total regression of all signs. When zinc therapy was interrupted, the manifestations reappeared and disappeared again when treatment was resumed. A defect of genetic origin in digestive zinc absorption is suggested. Mohnahan's advocated zinc treatment of acrodermatitis enteropathica in 1973; it is a non-toxic treatment, which is always active and be considered as a diagnostic test.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D008661	Metabolism, Inborn Errors	Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero.	Inborn Errors of Metabolism,Metabolism Errors, Inborn,Error, Inborn Metabolism,Errors Metabolism, Inborn,Errors Metabolisms, Inborn,Errors, Inborn Metabolism,Inborn Errors Metabolism,Inborn Errors Metabolisms,Inborn Metabolism Error,Inborn Metabolism Errors,Metabolism Error, Inborn,Metabolism Inborn Error,Metabolism Inborn Errors,Metabolisms, Inborn Errors
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000169	Acrodermatitis	Inflammation involving the skin of the extremities, especially the hands and feet. Several forms are known, some idiopathic and some hereditary. The infantile form is called Gianotti-Crosti syndrome.	Gianotti-Crosti Syndrome,Infantile Papular Acrodermatitis,Acrodermatitis Papulosa Infantum,Acropapulo-Vesicular Syndrome,Erythemato-Vesiculo-Papulous Eruptive Syndrome,Papular Acrodermatitis of Childhood,Papulovesicular Acrolocated Syndrome,Acrodermatitides,Acrodermatitis Papulosa Infantums,Acropapulo Vesicular Syndrome,Acropapulo-Vesicular Syndromes,Childhood Papular Acrodermatitides,Childhood Papular Acrodermatitis,Erythemato Vesiculo Papulous Eruptive Syndrome,Erythemato-Vesiculo-Papulous Eruptive Syndromes,Gianotti Crosti Syndrome,Infantile Papular Acrodermatitides,Papular Acrodermatitides, Infantile,Papular Acrodermatitis, Infantile,Papulovesicular Acrolocated Syndromes,Syndrome, Acropapulo-Vesicular,Syndrome, Erythemato-Vesiculo-Papulous Eruptive,Syndrome, Gianotti-Crosti,Syndromes, Acropapulo-Vesicular,Syndromes, Erythemato-Vesiculo-Papulous Eruptive,Syndromes, Papulovesicular Acrolocated
D015032	Zinc	A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.