Biomaterial Database

[Clinical evaluation of the antidepressive agent noveril]. 1982

M P Nevskiĭ, and V G Zaika, and Iu S Makliakov

Altogether 32 patients with different depressive states received noveril. The drug was administered in the doses of 180, 160, 240 and 320 mg in the first half of the day. Complete egress from the depressive state and considerable improvement were observed in 46% of the patients, slight improvement in 38% and no visible improvement was recorded in 16% of the patients. The data obtained enable the assessment of noveril as a primarily activation antidepressant with a rapid manifestation of therapeutic effect. The drug is indicated in classical depressions, adynamic subdepressions, obsessional depressions and cyclothymic subdepressions. The drugs are used in the doses about 160-240 mg. It was established that noveril should be used with caution in patients with arterial pressure fluctuations. In senesthopathic and hypochondriac conditions, noveril is either ineffective or leads to the patients' state deterioration.

UI	MeSH Term	Description	Entries
D001794	Blood Pressure	PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.	Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D003527	Cyclothymic Disorder	An affective disorder characterized by periods of depression and hypomania. These may be separated by periods of normal mood.	Cyclothymia,Cyclothymic Personality,Cyclothymic Disorders,Cyclothymic Personalities,Disorder, Cyclothymic,Personality, Cyclothymic
D003866	Depressive Disorder	An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.	Depression, Endogenous,Depression, Neurotic,Depression, Unipolar,Depressive Syndrome,Melancholia,Neurosis, Depressive,Unipolar Depression,Depressions, Endogenous,Depressions, Neurotic,Depressions, Unipolar,Depressive Disorders,Depressive Neuroses,Depressive Neurosis,Depressive Syndromes,Disorder, Depressive,Disorders, Depressive,Endogenous Depression,Endogenous Depressions,Melancholias,Neuroses, Depressive,Neurotic Depression,Neurotic Depressions,Syndrome, Depressive,Syndromes, Depressive,Unipolar Depressions
D003984	Dibenzazepines	Compounds with two BENZENE rings fused to AZEPINES.
D004305	Dose-Response Relationship, Drug	The relationship between the dose of an administered drug and the response of the organism to the drug.	Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D019964	Mood Disorders	Those disorders that have a disturbance in mood as their predominant feature.	Affective Disorders,Affective Disorder,Disorder, Affective,Disorder, Mood,Disorders, Affective,Disorders, Mood,Mood Disorder