-transparent.png){kind=logo}
The anxiolytic properties of buspirone were assessed in a 4-week double-blind study in 240 anxious patients, 81 of whom received buspirone, 81 diazepam, and 78 placebo. Patients were required to have scores greater than or equal to 9 on the Covi and greater than or equal to 18 on the Hamilton Rating Scale for Anxiety, and to endorse at least 5 items on a 17-item Anxiety Entry Checklist. Among 212 evaluable patients, those who improved most were married, well-educated females who had both a positive family adjustment and a low level of depression. Diazepam produced relatively equal improvement in females and males. Diazepam seems more effective in reducing somatic symptoms, while buspirone appears more effective in reducing symptoms associated with cognitive and interpersonal problems. Main differences between the drugs were seen in side effect profiles.
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
April 1990,
Indian journal of psychiatry,
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
January 1987,
Progress in neuro-psychopharmacology & biological psychiatry,
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
October 1980,
Journal of clinical pharmacology,
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
January 1985,
Pharmacotherapy,
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
November 2009,
Pharmacology, biochemistry, and behavior,
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
June 1987,
Journal of clinical psychopharmacology,
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
September 1979,
The American journal of psychiatry,
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
August 1990,
The British journal of psychiatry : the journal of mental science,
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
December 1986,
International journal of clinical pharmacology, therapy, and toxicology,
K Rickels, and
K Weisman, and
N Norstad, and
M Singer, and
D Stoltz, and
A Brown, and
J Danton
June 1987,
Canadian journal of psychiatry. Revue canadienne de psychiatrie,
