-transparent.png){kind=logo}
Adult rats submitted to perinatal protein deprivation (from day 14 of fetal life till 50 days of age) followed by a longer phase of nutritional recovery on balanced laboratory chow, showed a significant decrease of the pressor response elicited by noradrenaline and adrenaline, an effect that persisted after ganglionic blockade by hexamethonium. However, the effects of serotonin, acetylcholine, angiotensin II and vasopressin on blood pressure did not differ from those in the controls. Cumulative dose-response curves to noradrenaline and methoxamine on the circular contraction of isolated iliac arteries showed a significant shift to the right, together with a reduction in the maximal contraction. No significant difference in the maximal contraction elicited by Ba2+ was observed in experimental preparations as compared with controls. These results suggest the development of a specific subsensitivity to sympathetic drugs in the vascular bed as a consequence on undernutrition during perinatal life.
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
March 1986,
Pharmacology, biochemistry, and behavior,
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
August 1989,
Behavioural brain research,
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
January 1988,
Physiology & behavior,
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
May 1997,
The Journal of nutrition,
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
January 2007,
Life sciences,
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
December 1990,
Pharmacology, biochemistry, and behavior,
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
June 1979,
The Journal of nutrition,
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
August 1997,
Pharmacology, biochemistry, and behavior,
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
April 1994,
Pharmacology, biochemistry, and behavior,
P Del Basso, and
E A Keller, and
C Salica, and
O A Orsingher
June 1998,
Brain research bulletin,
