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An experimental study in dogs with intact thoracic cavity under morphine-chloralose narcosis featured coronary catheterization, extracorporeal perfusion and resistography as well as catheterization of the heart cavities and the coronary sinus. Hemodynamic and respiratory parameters were recorded simultaneously. PO2, PCO2 and pH were measured in the inflowing and outflowing blood. The effect of insulin on circulatory response in acute hypoxic hypoxia was examined before and after obsidan block of beta-adrenoreactive systems. Insulin administered after the obsidan beta-adrenergic block was found to limit coronary dilatation and reduce myocardial oxygen consumption in a more pronounced measure. It is suggested that the effect of insulin on coronary dilatation is due to reduced myocardial oxygen consumption resulting from its action on the heart's beta-adrenergic systems.
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
November 1971,
Kardiologiia,
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
January 1980,
Archivos del Instituto de Cardiologia de Mexico,
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
January 1971,
Naunyn-Schmiedebergs Archiv fur Pharmakologie,
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
December 1972,
Folia endocrinologica,
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
December 1971,
Medizinische Klinik,
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
April 1971,
La Presse medicale,
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
January 1982,
Terapevticheskii arkhiv,
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
May 1978,
Nihon rinsho. Japanese journal of clinical medicine,
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
February 1975,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
A I Khomaziuk, and
L F Iakusheva, and
L A Iavorskiĭ, and
A P Neshcheret
March 1969,
Terapevticheskii arkhiv,
