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Dehydroepiandrosterone sulfate (DEAS), a major adrenal product, is quantitatively one of the most important steroids found in human testicular tissue. However, conflicting data have been reported about the testicular production of DEAS 'in vivo'. We have measured the spermatic and peripheral concentrations of testosterone (T) and DEAS in two groups of prepubertal (Group I, N = 18) and pubertal (Group II; N = 11) boys undergoing surgery for undescended testis, inguinal hernia or varicocele. Mean (+/- SE) spermatic concentrations of DEAS (77 +/- 16 and 113 +/- 19 micrograms/dl in Group I and II respectively) were not significantly different from peripheral concentrations (70 +/- 13 and 130 +/- 16 micrograms/dl in Group I and II respectively). Mean spermatic concentrations of T (153 +/- 101 and 7515 +/- 4314 ng/dl in Group I and II respectively) were significantly different from peripheral concentrations (9 +/- 1 and 149 +/- 53 ng/dl; P less than 0.001 in both groups). Spermatic and peripheral levels of T and DEAS found in prepubertal boys were significantly lower than those found in pubertal boys. Spermatic levels of DEAS were not significantly related with spermatic levels of T in both groups. Our data show that, as in adult subjects, no significant spermatic-peripheral DEAS gradient is present in prepubertal and pubertal boys.
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
November 1992,
Acta endocrinologica,
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
February 1981,
International journal of andrology,
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
October 1981,
The Journal of clinical endocrinology and metabolism,
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
January 1981,
Journal of endocrinological investigation,
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
December 2014,
Environment international,
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
July 1971,
The Journal of endocrinology,
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
June 1983,
Clinical chemistry,
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
October 1981,
Nihon Sanka Fujinka Gakkai zasshi,
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
January 1977,
Archives francaises de pediatrie,
G Forti, and
F Facchinetti, and
S Sardelli, and
S Santoro, and
G A Grisolia, and
F Bassi, and
M Serio
January 2010,
Archives of gerontology and geriatrics,
