Biomaterial Database

Thyroidal iodine and thyroglobulin in hibernating and active Richardson's ground squirrels Spermophilus richardsoni. 1983

B A Demeneix, and F Lachiver, and N E Henderson

Thyroidal iodine, protein and thyroglobulin (TG) were investigated in a hibernator, Spermophilus richardsoni, sampled in the field and from laboratory-held winter colonies. In field animals, thyroidal iodine and protein contents were similar at onset of hibernation and at terminal arousal. Iodine content was increased in laboratory-held animals, a function of alimentary supply, but no differences were observed between hibernators and non-hibernators. Density sucrose gradients showed that approx. 20% of the TG was present as the 12S precursor sub-unit. No variations in the iodine content, nor the iodoamino acid composition of the TG occurred as a function of hibernation.

UI	MeSH Term	Description	Entries
D007454	Iodides	Inorganic binary compounds of iodine or the I- ion.	Iodide
D007455	Iodine	A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.	Iodine-127,Iodine 127
D009929	Organ Size	The measurement of an organ in volume, mass, or heaviness.	Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D011506	Proteins	Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.	Gene Products, Protein,Gene Proteins,Protein,Protein Gene Products,Proteins, Gene
D006605	Hibernation	The dormant state in which some warm-blooded animal species pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs.	Hibernation, Artificial,Induced Hibernation,Artificial Hibernation,Artificial Hibernations,Hibernation, Induced,Hibernations,Induced Hibernations
D000596	Amino Acids	Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.	Amino Acid,Acid, Amino,Acids, Amino
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001143	Arousal	Cortical vigilance or readiness of tone, presumed to be in response to sensory stimulation via the reticular activating system.	Vigilance, Cortical,Arousals,Cortical Vigilance
D012589	Sciuridae	A family of the order Rodentia which contains 49 genera. Some of the more common genera are MARMOTA, which includes the marmot and woodchuck; Sciurus, the gray squirrel, S. carolinensis, and the fox squirrel, S. niger; Tamias, the eastern and western chipmunk; and Tamiasciurus, the red squirrel. The flying squirrels, except the scaly-tailed Anomaluridae, also belong to this family.	Chipmunks,Citellus,Eutamias,Prairie Dogs,Spermophilus,Squirrels,Susliks,Tamias,Chipmunk,Dog, Prairie,Dogs, Prairie,Prairie Dog,Squirrel,Suslik
D013954	Thyroglobulin