-transparent.png){kind=logo}
Tissue transglutaminase accumulates rapidly and to very high levels (1-2% of cellular protein) in mouse peritoneal macrophages cultured in mouse serum. The induction is due to accelerated synthesis of the enzyme (150-fold increase) that occurs within 90 min of exposure of the cells to a heat-labile constituent of serum or plasma. The induction is reversible and is not reproduced by known activators of macrophage function such as lipopolysaccharide, muramyl dipeptide, and tuftsin. In animals, elevated levels of tissue transglutaminase are also found in inflammatory macrophages elicited by thioglycolate broth.
Related Publications
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
October 1984,
The Journal of biological chemistry,
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
September 1994,
Biochemical and biophysical research communications,
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
January 1989,
Microbiology and immunology,
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
December 2000,
Biological & pharmaceutical bulletin,
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
March 1987,
The Journal of experimental medicine,
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
June 1994,
Journal of biochemistry,
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
August 2017,
Cytotechnology,
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
September 1988,
Journal of biochemistry,
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
June 1978,
Journal of the Reticuloendothelial Society,
M P Murtaugh, and
K Mehta, and
J Johnson, and
M Myers, and
R L Juliano, and
P J Davies
January 1986,
The Journal of biological chemistry,
