The control programs of mosquitoes are physical; chemical, mechanic control, control by sterilization, genetic, public health rules and biological control. Biological control is the most efficient and convenient one because of resistant organisms against insecticides, economic problems and degeneration of the eco-system. This control employs protozoal, fungal, bacterial pathogens, mosquito predator fish, nematoda parasites as bioagents. Safety tests, sensitivity to environmental factors, effectiveness against non-target organisms, production, stability and field trials are all giving promising results.