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The present investigation assessed 45 anxious neurotic adult patients treated double-blindly in three randomized drug groups; bromazepam, diazepam and placebo. Non-signal, simple and complex signal stimuli were presented to monitor electrodermal activity changes at baseline, 4 h, 1 week and 14 days of treatment. The results indicate that patients with generalized anxiety disorder treated with bromazepam developed decreased skin conductance during the presentation of visual, auditory, and tactile stimuli presentations. Such skin conductance changes were not significant for patients on diazepam and placebo. Future clinical and research implications of these perceptual and psychophysiological results are discussed in conjunction with the usage of a functional-realistic-instrumental paradigm rather than studying anxiety on an attentional-arousal continuum.
Y D Lapierre, and
H J Butter, and
L K Oyewumi
February 2002,
The American journal of psychiatry,
Y D Lapierre, and
H J Butter, and
L K Oyewumi
August 2013,
Journal of anxiety disorders,
Y D Lapierre, and
H J Butter, and
L K Oyewumi
August 1985,
Biological psychiatry,
Y D Lapierre, and
H J Butter, and
L K Oyewumi
September 2003,
The British journal of clinical psychology,
Y D Lapierre, and
H J Butter, and
L K Oyewumi
October 2002,
American family physician,
Y D Lapierre, and
H J Butter, and
L K Oyewumi
May 2009,
American family physician,
Y D Lapierre, and
H J Butter, and
L K Oyewumi
March 2020,
The Journal of the American Osteopathic Association,
Y D Lapierre, and
H J Butter, and
L K Oyewumi
January 1997,
Molecular psychiatry,
Y D Lapierre, and
H J Butter, and
L K Oyewumi
February 1999,
Psychoneuroendocrinology,
Y D Lapierre, and
H J Butter, and
L K Oyewumi
February 2000,
The Journal of clinical psychiatry,
