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A patient was recently observed who was a carrier simultaneously of the HBs antigen and the HBs antibody after hepatitis. He presented with a multisystem disease affecting the peripheral nervous system, the prostate and the bladder. Biopsy of these two latter organs demonstrated necrotizing vasculitis compatible with periarteritis nodosa. An atypical immunological response to the hepatitis B virus, as found in our patient, may induce extrahepatic lesions.
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