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We have studied human renin messenger RNA by hybridization with the mouse submaxillary gland (SMG) renin cDNA probe. The human kidney messenger RNA is about 1.6 kilobase (kb) long, similarly to the mouse SMG renin mRNA. A kidney renin cDNA clone of 1.1 kb length was obtained. A comparison of nucleotide sequences of mouse and human cDNA clones reveals conservation of residues involved in catalytic mechanisms and a potential glycosylation site. The human renin molecular probe allowed us to study renin expression in human chorionic tissue. The chorionic and kidney renin messenger RNAs are similar in length. The Southern blot analysis reveals the presence of a single renin gene in human DNA.
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
November 1985,
Proceedings of the National Academy of Sciences of the United States of America,
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
January 1989,
Biochemical and biophysical research communications,
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
October 1981,
Proceedings of the National Academy of Sciences of the United States of America,
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
July 1986,
The Journal of biological chemistry,
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
January 1987,
Proceedings of the National Academy of Sciences of the United States of America,
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
April 1993,
Experimental eye research,
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
January 1986,
Gene,
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
January 1990,
Doklady Akademii nauk SSSR,
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
September 1986,
Proceedings of the National Academy of Sciences of the United States of America,
F Soubrier, and
J J Panthier, and
P Corvol, and
F Rougeon
January 1987,
Gene,
