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A knowledge of the response of prolactin secretion to drug stimulation is required for the better understanding of infertility associated with hyperprolactinemic states. The dynamics of prolactin secretion was investigated in 30 ovulatory females subjected to sulpiride stimulation. Prolonged dynamic tests are inappropriate procedures for screening purposes and basal value determinations present a weak correlation with the curve area (rs = 0.485; P less than 0.005). On the contrary, a high statistical correlation (rs = 0.861; P less than 0.001) was found between the curve area and the hormonal value 30 min after sulpiride administration. We conclude that basal prolactin levels and the 30-min value after sulpiride administration seem to be sufficient and valid representative estimations in the screening of abnormal prolactin secretion states.
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
January 1984,
Acta obstetricia et gynecologica Scandinavica,
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
January 1979,
Neuroendocrinology,
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
October 1977,
The Journal of clinical endocrinology and metabolism,
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
March 1994,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
May 2000,
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
December 1986,
The Journal of reproductive medicine,
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
January 1983,
Gynecologic and obstetric investigation,
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
August 1987,
British journal of clinical pharmacology,
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
November 1982,
Obstetrics and gynecology,
C R Nahoum, and
J A Pantaleão, and
R R Freire, and
S Franco
April 1989,
Obstetrics and gynecology,
