Ivermectin in onchocerciasis. 1984

J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac

UI MeSH Term Description Entries
D007559 Ivermectin A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form. Eqvalan,Ivomec,MK-933,Mectizan,Stromectol,MK 933,MK933
D007783 Lactones Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure. Large cyclic lactones of over a dozen atoms are MACROLIDES. Lactone
D009855 Onchocerciasis Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions. Onchocerciases
D005369 Filaricides Pharmacological agents destructive to nematodes in the superfamily Filarioidea.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000871 Anthelmintics Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. Anthelmintic,Antihelmintic,Vermifuge,Vermifuges,Antihelmintics

Related Publications

J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
October 1984, Lancet (London, England),
J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
November 1984, Lancet (London, England),
J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
December 1982, Lancet (London, England),
J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
November 1982, Lancet (London, England),
J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
November 1989, Australian and New Zealand journal of ophthalmology,
J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
February 1999, Lancet (London, England),
J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
January 1996, World health forum,
J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
January 1990, Acta Leidensia,
J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
January 1992, Documenta ophthalmologica. Advances in ophthalmology,
J P Coulaud, and M Lariviere, and M A Aziz, and M C Gervais, and P Gaxotte, and A M Deluol, and J Cenac
January 1990, Acta Leidensia,
Copied contents to your clipboard!