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The activity of gamma-glutamyl transferase (GGT) in the liver of 22 patients with alcoholic liver disease, 24 with nonalcoholic liver disease and 12 normal controls was measured. The enhanced hepatic GGT activity was higher in alcoholic patients and nonalcoholic patients than in the normal controls. No statistical significance of difference could be found in hepatic GGT activity between alcoholic and nonalcoholic patients, while serum GGT activity was markedly elevated in alcoholic patients compared to nonalcoholic patients. There was better correlation between hepatic and serum GGT activity in alcoholic patients. Furthermore the enhanced hepatic GGT activity could contribute to the pathogenesis of liver fibrosis as a result of the investigation for hepatic GGT activity and histological liver fibrosis.
M Yamauchi, and
K Kimura, and
H Kawase, and
Y Watanabe, and
T Kitahara, and
K Ogura, and
K Fujisawa, and
H Kameda
August 2020,
Journal of clinical medicine research,
M Yamauchi, and
K Kimura, and
H Kawase, and
Y Watanabe, and
T Kitahara, and
K Ogura, and
K Fujisawa, and
H Kameda
October 2023,
Journal of gastroenterology and hepatology,
M Yamauchi, and
K Kimura, and
H Kawase, and
Y Watanabe, and
T Kitahara, and
K Ogura, and
K Fujisawa, and
H Kameda
January 1997,
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M Yamauchi, and
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H Kameda
January 2016,
Clinica chimica acta; international journal of clinical chemistry,
M Yamauchi, and
K Kimura, and
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H Kameda
December 2016,
Annals of translational medicine,
M Yamauchi, and
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H Kameda
October 2006,
Obesity surgery,
M Yamauchi, and
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H Kawase, and
Y Watanabe, and
T Kitahara, and
K Ogura, and
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H Kameda
January 2011,
Journal of biological regulators and homeostatic agents,
M Yamauchi, and
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Y Watanabe, and
T Kitahara, and
K Ogura, and
K Fujisawa, and
H Kameda
May 1983,
Scandinavian journal of gastroenterology,
M Yamauchi, and
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H Kameda
April 2022,
European journal of clinical investigation,
M Yamauchi, and
K Kimura, and
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H Kameda
February 2017,
Clinica chimica acta; international journal of clinical chemistry,
