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The therapeutic activity of tryptophan and the serotonin blood level in epileptic patients were studied. A group of patients (24 cases) received tryptophan (a source of serotonin synthesis in the organism per os during three weeks in a dose of 0,25 g thrice daily. The studies demonstrated the decreased initial level of blood serotonin in patients, especially in those with frequent epileptic seizures and with the disease of long standing. The intake of tryptophan even after a week of its administration produced a reliable increase in the level of blood serotonin and suggestive changes in the clinical picture. This was especially noticeable in patients with seizures of the grand mal tupe and personality changes.
T S Avanesova, and
E I Sviridova
April 1972,
Archives of general psychiatry,
T S Avanesova, and
E I Sviridova
September 1969,
Annals of the New York Academy of Sciences,
T S Avanesova, and
E I Sviridova
March 1978,
Endocrinologia experimentalis,
T S Avanesova, and
E I Sviridova
January 1975,
Acta vitaminologica et enzymologica,
T S Avanesova, and
E I Sviridova
August 1979,
Zeitschrift fur Orthopadie und ihre Grenzgebiete,
T S Avanesova, and
E I Sviridova
June 1967,
Archives of disease in childhood,
T S Avanesova, and
E I Sviridova
January 1977,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
T S Avanesova, and
E I Sviridova
May 1974,
Journal of neurochemistry,
T S Avanesova, and
E I Sviridova
January 1984,
Neurochemistry international,
T S Avanesova, and
E I Sviridova
June 1982,
Neuropharmacology,
