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To determine the effect of prolonged administration of exogenous interferon on the autoimmune disease of NZB/W female mice, forty-four NZB/W mice received three injections per week of 6.4 x 10(4) interferon units from birth to 33 weeks, forty mice were injected with mock interferon and forty-eight mice were left untreated. In mice injected with interferon growth was delayed, survival was decreased, and the severity of the glomerulonephritis was enhanced. Interferon increased the titre of serum anti-ssDNA and anti-soluble nucleoprotein antibodies, but had no effect on the circulating immune complex load. These results suggest that interferon in some way affects local deposition of immune complexes within the glomerulus.
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
June 2003,
Journal of immunology (Baltimore, Md. : 1950),
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
October 2000,
Scandinavian journal of immunology,
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
January 1992,
Autoimmunity,
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
September 1989,
Biochimica et biophysica acta,
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
January 1984,
Voprosy virusologii,
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
June 1998,
Clinical and experimental immunology,
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
April 1982,
Fysiatricky a reumatologicky vestnik,
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
April 1997,
The British journal of nutrition,
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
September 1993,
Clinical and experimental immunology,
C Adam, and
Y Thoua, and
P Ronco, and
P Verroust, and
M Tovey, and
L Morel-Maroger
December 2022,
Arthritis research & therapy,
