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Peripheral blood lymphocytes from MS patients and from healthy control donors were compared for their ability to mediate spontaneous and antibody-dependent cell-mediated cytotoxicity. They were also compared for their ability to respond to infection with various strains of measles and sSPE viruses with interferon production and enhanced NK activity. Neither SLMC nor ADCC against several different target cells was found to be impaired in the MS population. Furthermore, no defect was detected in the response of patients' lymphocytes to virus challenge in vitro in terms of both activation of NK cells and interferon production. Enhanced NK activity was also induced by an exogenous interferon preparation and by Poly I:C to the same extent in patients and controls.
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W Hall, and
L Kastrukoff, and
R P Lisak, and
B Perussia, and
G Trinchieri, and
H Koprowski
May 1983,
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D Santoli, and
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R P Lisak, and
B Perussia, and
G Trinchieri, and
H Koprowski
January 1984,
Annals of the New York Academy of Sciences,
D Santoli, and
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B Perussia, and
G Trinchieri, and
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July 1988,
[Hokkaido igaku zasshi] The Hokkaido journal of medical science,
D Santoli, and
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G Trinchieri, and
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September 1985,
Infection and immunity,
D Santoli, and
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L Kastrukoff, and
R P Lisak, and
B Perussia, and
G Trinchieri, and
H Koprowski
February 2000,
Multiple sclerosis (Houndmills, Basingstoke, England),
D Santoli, and
W Hall, and
L Kastrukoff, and
R P Lisak, and
B Perussia, and
G Trinchieri, and
H Koprowski
January 1995,
Multiple sclerosis (Houndmills, Basingstoke, England),
D Santoli, and
W Hall, and
L Kastrukoff, and
R P Lisak, and
B Perussia, and
G Trinchieri, and
H Koprowski
July 1997,
Journal of clinical immunology,
D Santoli, and
W Hall, and
L Kastrukoff, and
R P Lisak, and
B Perussia, and
G Trinchieri, and
H Koprowski
July 1983,
Journal of the neurological sciences,
D Santoli, and
W Hall, and
L Kastrukoff, and
R P Lisak, and
B Perussia, and
G Trinchieri, and
H Koprowski
January 1987,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
D Santoli, and
W Hall, and
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R P Lisak, and
B Perussia, and
G Trinchieri, and
H Koprowski
January 1974,
Arthritis and rheumatism,
