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Xenon photocoagulation burns in the rabbit fundus were studied angiographically with fluorescein labelled dextrans of molecular weights in the range 3000 to 150 000. Recent photocoagulation burns showed dye leakage to all molecular weights used. Angiograms 2 days after burns had been produced showed leakage of dextrans of molecular weights up to and including 70 000 but no leakage of dextran of 150 000 molecular weight. At 7 days after photocoagulation healed burns remained permeable to dextrans of molecular weight 3000 or 20 000, but in the majority of eyes such burns did not leak dextrans of over 40 000 molecular weight. The clinical significance of the selective nature of photocoagulative damage to the posterior blood ocular barrier is discussed.
E I McNaught, and
W S Foulds, and
N F Johnson
June 1977,
Experimental eye research,
E I McNaught, and
W S Foulds, and
N F Johnson
October 1975,
Acta neuropathologica,
E I McNaught, and
W S Foulds, and
N F Johnson
February 1979,
Experientia,
E I McNaught, and
W S Foulds, and
N F Johnson
September 1977,
Transactions of the ophthalmological societies of the United Kingdom,
E I McNaught, and
W S Foulds, and
N F Johnson
January 1980,
Archives of dermatological research,
E I McNaught, and
W S Foulds, and
N F Johnson
August 1981,
Investigative ophthalmology & visual science,
E I McNaught, and
W S Foulds, and
N F Johnson
February 1992,
The British journal of ophthalmology,
E I McNaught, and
W S Foulds, and
N F Johnson
January 1995,
Epithelial cell biology,
E I McNaught, and
W S Foulds, and
N F Johnson
August 2001,
Acta ophthalmologica Scandinavica,
E I McNaught, and
W S Foulds, and
N F Johnson
September 1978,
Investigative ophthalmology & visual science,
