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Mice were injected from day of birth onward with rabbit anti-mouse IgM antiserum or purified rabbit anti-mouse IgM antibodies. These mice completely lacked Ig-positive cells or serum Ig, as analyzed by specific fluoresceinated antibodies on the fluorescence-activated cell sorter (FACS-II), by polyclonal B cell mitogens and by specific precipitation in agar. These animals were then primed in vivo by antigen emulsified in complete Freund's adjuvant, and, subsequently, their draining lymph nodes were tested for their T cell proliferative responses in vitro, to the relevant antigen and were found to be severely impaired. However, the antigen-presenting capacity of both spleen cells and thioglycollate-induced peritoneal cells was found to be intact.
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
January 1990,
The Journal of molecular and cellular immunology : JMCI,
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
April 1988,
Immunology,
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
January 1990,
International immunology,
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
August 1985,
Cellular immunology,
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
January 1994,
Archivum immunologiae et therapiae experimentalis,
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
October 1994,
The Journal of clinical investigation,
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
November 1984,
Journal of immunology (Baltimore, Md. : 1950),
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
December 1983,
Journal of immunology (Baltimore, Md. : 1950),
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
December 1996,
Journal of immunology (Baltimore, Md. : 1950),
Y Ron, and
P De Baetselier, and
J Gordon, and
M Feldman, and
S Segal
April 2006,
Journal of immunology (Baltimore, Md. : 1950),
