Sources of variability in auditory brain stem evoked potential measures over time. 1982

R M Edwards, and J S Buchwald, and P E Tanguay, and J A Schwafel

Auditory brain stem EPs elicited in 10 normal adults by monaural clicks delivered at 72 dB HL, 20/sec showed no significant change in wave latencies or in the ratio of wave I to wave Y amplitude across 250 trial subsets, across 250 trial subsets, across 1500 trial blocks within a test session, or across two test sessions separated by several months. Sources of maximum variability were determined by using mean squared differences with all but one condition constant. 'Subjects' was shown to contribute the most variability followed by 'ears', 'sessions' and 'runs'; collapsing across conditions, wave III latencies were found to be the least variable, while wave II showed the most variability. Some EP morphologies showed extra peaks between waves II and IV, missing wave IV or wave IV fused with wave V. Such variations in wave form morphology were independent of EMG amplitude and were characteristic of certain individuals.

UI MeSH Term Description Entries
D008297 Male Males
D011930 Reaction Time The time from the onset of a stimulus until a response is observed. Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D001933 Brain Stem The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA. Brainstem,Truncus Cerebri,Brain Stems,Brainstems,Cerebri, Truncus,Cerebrus, Truncus,Truncus Cerebrus
D005072 Evoked Potentials, Auditory The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS. Auditory Evoked Potentials,Auditory Evoked Response,Auditory Evoked Potential,Auditory Evoked Responses,Evoked Potential, Auditory,Evoked Response, Auditory,Evoked Responses, Auditory,Potentials, Auditory Evoked
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000704 Analysis of Variance A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable. ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

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