-transparent.png){kind=logo}
1. Blood pressure was monitored continuously in conscious rats with chronic Goldblatt two-kidney, one-clip hypertension. 2. Hypertension was rapidly reversed by removal of the constricting clip and the reversal was complete by 12 h, although structural vascular changes persisted for much longer. 3. Blood pressure in this model of hypertension was not affected by a 15 h infusion of either indomethacin or aprotinin. 4. The pattern of fall in blood pressure after removal of the clip was similar when animals were infused with either indomethacin or aprotinin. Blood pressure at 24 h was normal and did not differ significantly from that of unclipped rats given a glucose infusion. 5. The fall in blood pressure produced by unclipping therefore did not appear to be mediated via the prostaglandin or kallikrein systems.
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
January 1980,
Hypertension (Dallas, Tex. : 1979),
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
January 1991,
American journal of hypertension,
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
January 1993,
Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia,
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
August 1983,
Journal of hypertension,
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
December 1985,
Journal of hypertension,
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
October 1985,
Kidney international,
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
January 1984,
Clinical and experimental pharmacology & physiology,
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
December 1986,
Prostaglandins, leukotrienes, and medicine,
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
April 1997,
Hypertension (Dallas, Tex. : 1979),
G I Russell, and
R F Bing, and
J D Swales, and
H Thurston
July 2002,
Acta physiologica Scandinavica,
