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This study was performed on patients (n = 18) suffering from strictly defined hyperdynamic septic shock. Plasma factors (C-reactive protein, acid alpha 1-glycoprotein, fibrinogen, fibrinopeptide A, fibrinogen-fibrin split products, factor XIII, antithrombin III, complement factors C3 and C4, inter-alpha-trypsin-inhibitor and alpha 2-macroglobulin) measured during hyperdynamic septic shock were highly abnormal. The activation and consumption of clotting, fibrinolytic and complement factors due to system-specific proteinases (such as thrombokinase or plasminogen activators) seemed to be intensified by the nonspecific proteolytic activity of granulocytic proteinases probably released by the action of endotoxins. Possible therapeutic measures to maintain the endogeneous defence mechanism against enhanced proteolysis during septic shock are discussed.
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
May 1992,
Minerva anestesiologica,
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
January 1984,
Intensive care medicine,
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
May 1997,
Intensive care medicine,
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
January 1974,
Triangle; the Sandoz journal of medical science,
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
January 1987,
Critical care medicine,
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
June 1993,
Chest,
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
April 1982,
Masui. The Japanese journal of anesthesiology,
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
October 2003,
Critical care medicine,
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
February 2016,
Annals of the American Thoracic Society,
J Witte, and
M Jochum, and
R Scherer, and
W Schramm, and
K Hochstrasser, and
H Fritz
May 2006,
Intensive care medicine,
