Biomaterial Database

Onychotillomania treated with pimozide (Orap). 1982

K Hamann

A case of onychotillomania in a 70-year-old woman is presented. The disease had persisted for 51/2 years. All her fingernails were plucked away. The patient had a fixed hypochondrial delusion of nail disease. After treatment with pimozide (Orap) for 7 months the nails were normal.

UI	MeSH Term	Description	Entries
D006998	Hypochondriasis	Preoccupation with the fear of having, or the idea that one has, a serious disease based on the person's misinterpretation of bodily symptoms. (APA, DSM-IV)	Neurosis, Hypochondriacal,Hypochondriacal Neuroses,Hypochondriacal Neurosis
D009262	Nails	The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.	Fingernails,Toenails,Fingernail,Nail,Toenail
D010868	Pimozide	A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)	Antalon,Orap,Orap forte,R-6238,R6238
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly