Comparison of serum and urine hCG levels with SP1 and PAPP-A levels in patients with first-trimester vaginal bleeding. 1983

G M Masson, and F Anthony, and M S Wilson, and K Lindsay

Serum levels of human chorionic gonadotropin (hCG) in patients with threatened abortion are compared to the values in normal pregnancy. The predictive value was 93%, the sensitivity was 84%, and the prediction of gestational viability was 81% for the threatened group. These results compare favorably with urinary pregnancy testing and are similar to those obtained with the assay of Schwangerschaftsprotein I. Human chorionic gonadotropin was, however, a much better predictor of pregnancy outcome than pregnancy-associated plasma protein-A.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011257 Pregnancy Proteins Proteins produced by organs of the mother or the PLACENTA during PREGNANCY. These proteins may be pregnancy-specific (present only during pregnancy) or pregnancy-associated (present during pregnancy or under other conditions such as hormone therapy or certain malignancies.) Placental Proteins,Proteins, Placental,Proteins, Pregnancy
D011258 Pregnancy Tests Tests to determine whether or not an individual is pregnant. Pregnancy Test,Test, Pregnancy,Tests, Pregnancy
D011261 Pregnancy Trimester, First The beginning third of a human PREGNANCY, from the first day of the last normal menstrual period (MENSTRUATION) through the completion of 14 weeks (98 days) of gestation. Early Placental Phase,Pregnancy, First Trimester,Trimester, First,Early Placental Phases,First Pregnancy Trimester,First Pregnancy Trimesters,First Trimester,First Trimester Pregnancies,First Trimester Pregnancy,First Trimesters,Phase, Early Placental,Phases, Early Placental,Placental Phase, Early,Placental Phases, Early,Pregnancies, First Trimester,Pregnancy Trimesters, First,Trimesters, First
D011266 Pregnancy-Associated Plasma Protein-A A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa. PAPP-A,IGFBP-4 Metalloproteinase,IGFBP-4 Protease,IGFBP-4-Specific Proteinase,Insulin-Like Growth Factor-Dependent IGF Binding Protein-4 Protease,Insulin-Like-Growth Factor Binding Protein-4 Protease,PAPP-alpha,Pregnancy Associated alpha Plasma Protein,Pregnancy-Associated alpha-Plasma Protein,IGFBP 4 Metalloproteinase,IGFBP 4 Protease,Insulin Like Growth Factor Binding Protein 4 Protease,Insulin Like Growth Factor Dependent IGF Binding Protein 4 Protease,Metalloproteinase, IGFBP-4,PAPP alpha,Pregnancy Associated Plasma Protein A,Protease, IGFBP-4
D011268 Pregnancy-Specific beta 1-Glycoproteins Glycoproteins with the electrophoretic mobility of BETA-GLOBULINS, secreted by the placental TROPHOBLASTS into the maternal bloodstream during PREGNANCY. They can be detected 18 days after OVULATION and reach 200 mg/ml at the end of pregnancy. They are associated with fetal well-being. Pregnancy-Specific beta 1-Glycoprotein,SP1 Pregnancy Protein,Trophoblast-Specific beta 1-Glycoprotein,beta 1-Glycoprotein, Pregnancy-Specific,beta-1 Glycoprotein, Trophoblast-Specific,PAPP-B,PAPP-C,PSBG-1,Pregnancy Specific beta 1 Glycoprotein,Pregnancy Specific beta-1 Glycoprotein,Pregnancy Specific beta1-Glycoprotein.,Pregnancy-Associated Plasma Protein B,Pregnancy-Associated Plasma Protein C,Pregnancy-Associated beta-Plasma Protein,Pregnancy-Specific beta-1 Globulin,Schwangerschaftsprotein 1,Trophoblastic beta 1-Glycoprotein,Trophoblastic beta(1)-Globulin,Trophoblastic beta-Globulin,beta 1-Globulin, Trophoblast-Specific,1-Glycoproteins, Pregnancy-Specific beta,PAPP B,PSBG 1,Pregnancy Associated Plasma Protein B,Pregnancy Associated Plasma Protein C,Pregnancy Protein, SP1,Pregnancy Specific beta 1 Globulin,Pregnancy Specific beta 1 Glycoproteins,Protein, SP1 Pregnancy,Trophoblast Specific beta 1 Glycoprotein,Trophoblast-Specific beta 1-Globulin,Trophoblast-Specific beta-1 Glycoprotein,Trophoblastic beta Globulin,beta 1 Globulin, Trophoblast Specific,beta 1-Glycoproteins, Pregnancy-Specific,beta-1 Globulin, Pregnancy-Specific,beta-Globulin, Trophoblastic
D011336 Probability The study of chance processes or the relative frequency characterizing a chance process. Probabilities
D005260 Female Females
D005328 Fetal Viability The potential of the FETUS to survive outside the UTERUS after birth, natural or induced. Fetal viability depends largely on the FETAL ORGAN MATURITY, and environmental conditions. Viability, Fetal

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