BIOMAT Database Logo BIOMAT Database Logo

Radioautographic study of the axonal transport of proteins into the sensory nerve endings of avian mechanoreceptors. 1983

C N Chouchkov, and D V Markov, and G P Galabov

The axonal transport of proteins to the nerve endings of Herbst and Grandry sensory receptors has been investigated by electron-microscope radioautography. Soon after the injection of [3H]leucine into the trigeminal ganglia of young ducks, labeled proteins are conveyed along the suborbital sensory nerves to the sensory nerve endings at rates of at least 200-280 mm/day. Most of these rapidly transported proteins accumulate in areas containing vesicles of various kinds and along the axolemmal region. Later, the bulk of labeled proteins migrate along the axons at rates of about 15 mm/day and are distributed mainly to the mitochondria. A small portion of labeled material is transferred to the adjoining modified Schwann and specialized Grandry receptor cells. It is concluded that the transport of proteins from sensory ganglia to sensory nerve endings of mechanoreceptors is conveyed at fast and intermediate rates and is mainly used for the renewal of vesicles, axolemmal constituents and mitochondria.

UI MeSH Term Description Entries
D007930 Leucine An essential branched-chain amino acid important for hemoglobin formation. L-Leucine,Leucine, L-Isomer,L-Isomer Leucine,Leucine, L Isomer
D008465 Mechanoreceptors Cells specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. Mechanoreceptor cells include the INNER EAR hair cells, which mediate hearing and balance, and the various somatosensory receptors, often with non-neural accessory structures. Golgi Tendon Organ,Golgi Tendon Organs,Krause's End Bulb,Krause's End Bulbs,Mechanoreceptor,Mechanoreceptor Cell,Meissner's Corpuscle,Neurotendinous Spindle,Neurotendinous Spindles,Receptors, Stretch,Ruffini's Corpuscle,Ruffini's Corpuscles,Stretch Receptor,Stretch Receptors,Mechanoreceptor Cells,Bulb, Krause's End,Bulbs, Krause's End,Cell, Mechanoreceptor,Cells, Mechanoreceptor,Corpuscle, Meissner's,Corpuscle, Ruffini's,Corpuscles, Ruffini's,End Bulb, Krause's,End Bulbs, Krause's,Krause End Bulb,Krause End Bulbs,Krauses End Bulb,Krauses End Bulbs,Meissner Corpuscle,Meissners Corpuscle,Organ, Golgi Tendon,Organs, Golgi Tendon,Receptor, Stretch,Ruffini Corpuscle,Ruffini Corpuscles,Ruffinis Corpuscle,Ruffinis Corpuscles,Spindle, Neurotendinous,Spindles, Neurotendinous,Tendon Organ, Golgi,Tendon Organs, Golgi
D008854 Microscopy, Electron Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen. Electron Microscopy
D009412 Nerve Fibers Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM. Cerebellar Mossy Fibers,Mossy Fibers, Cerebellar,Cerebellar Mossy Fiber,Mossy Fiber, Cerebellar,Nerve Fiber
D009419 Nerve Tissue Proteins Proteins, Nerve Tissue,Tissue Proteins, Nerve
D004372 Ducks A water bird in the order Anseriformes (subfamily Anatinae (true ducks)) with a broad blunt bill, short legs, webbed feet, and a waddling gait. Duck
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001345 Autoradiography The making of a radiograph of an object or tissue by recording on a photographic plate the radiation emitted by radioactive material within the object. (Dorland, 27th ed) Radioautography
D001370 Axonal Transport The directed transport of ORGANELLES and molecules along nerve cell AXONS. Transport can be anterograde (from the cell body) or retrograde (toward the cell body). (Alberts et al., Molecular Biology of the Cell, 3d ed, pG3) Axoplasmic Flow,Axoplasmic Transport,Axoplasmic Streaming,Axonal Transports,Axoplasmic Flows,Axoplasmic Transports,Streaming, Axoplasmic,Transport, Axonal,Transport, Axoplasmic,Transports, Axonal,Transports, Axoplasmic
D012668 Trigeminal Ganglion The semilunar-shaped ganglion containing the cells of origin of most of the sensory fibers of the trigeminal nerve. It is situated within the dural cleft on the cerebral surface of the petrous portion of the temporal bone and gives off the ophthalmic, maxillary, and part of the mandibular nerves. Gasserian Ganglion,Semilunar Ganglion,Gasser's Ganglion,Trigeminal Ganglia,Ganglia, Trigeminal,Ganglion, Gasser's,Ganglion, Gasserian,Ganglion, Semilunar,Ganglion, Trigeminal,Gasser Ganglion,Gassers Ganglion,Semilunar Ganglions,Trigeminal Ganglias,Trigeminal Ganglions

Related Publications

C N Chouchkov, and D V Markov, and G P Galabov
Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2.
October 2021, Stem cell research,
C N Chouchkov, and D V Markov, and G P Galabov
Fine structure and axonal transport labeling of intraepithelial sensory nerve endings in anterior hard palate of the rat.
January 1983, Somatosensory research,
C N Chouchkov, and D V Markov, and G P Galabov
Slow axonal transport of labelled proteins in sensory fibres of rabbit vagus nerve.
June 1976, Journal of neurochemistry,
C N Chouchkov, and D V Markov, and G P Galabov
Retrograde axonal transport following injection of [3H]-serotonin into the olfactory bulb. II. Radioautographic study.
September 1980, Brain research,
C N Chouchkov, and D V Markov, and G P Galabov
Axonal transport of labeled material into sensory nerve ending of cat carotid body.
March 1977, Brain research,
C N Chouchkov, and D V Markov, and G P Galabov
Axonal transport of labelled proteins in sensory fibres of rabbit vagus nerve in vitro.
November 1975, Journal of neurochemistry,
C N Chouchkov, and D V Markov, and G P Galabov
Radioautographic study of incorporated proteins into chicken peripheral nerve myelin during development.
January 1982, Acta anatomica,
C N Chouchkov, and D V Markov, and G P Galabov
Study of the Nerve Endings and Mechanoreceptors of the Anterolateral Ligament of the Knee.
October 2019, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association,
C N Chouchkov, and D V Markov, and G P Galabov
Carrier-mediated transport of choline into synaptic nerve endings.
June 1969, The Journal of biological chemistry,
C N Chouchkov, and D V Markov, and G P Galabov
[Sensory nerve endings in the skin].
April 1993, No to shinkei = Brain and nerve,
Copied contents to your clipboard!