BIOMAT Database Logo BIOMAT Database Logo

[Trophoblastic beta-globulin in immunoglobulin preparations]. 1983

V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov

The content of trophoblastic beta-globulin in 142 lots of commercial immunoglobulin preparations from 20 manufacturers, produced from placental, abortion and donor blood sera, has been studied. 83% of lots from abortion blood serum and 94% of lots from placental blood serum have been found to contain the admixture of this beta-globulin, its concentration in the lots from placental blood serum being significantly higher. The method for the detection of trophoblastic beta-globulin may be used for evaluating the quality of immunoglobulin preparations as it indicates the degree of their purification from placental proteins.

UI MeSH Term Description Entries
D007136 Immunoglobulins Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses. Globulins, Immune,Immune Globulin,Immune Globulins,Immunoglobulin,Globulin, Immune
D010920 Placenta A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES). Placentoma, Normal,Placentome,Placentas,Placentomes
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D001789 Blood Group Antigens Sets of cell surface antigens located on BLOOD CELLS. They are usually membrane GLYCOPROTEINS or GLYCOLIPIDS that are antigenically distinguished by their carbohydrate moieties. Blood Group,Blood Group Antigen,Blood Groups,Antigen, Blood Group,Antigens, Blood Group,Group Antigen, Blood,Group, Blood,Groups, Blood
D005260 Female Females
D006063 Chorionic Gonadotropin A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN). Chorionic Gonadotropin, Human,HCG (Human Chorionic Gonadotropin),Biogonadil,Choriogonadotropin,Choriogonin,Chorulon,Gonabion,Human Chorionic Gonadotropin,Pregnyl,Gonadotropin, Chorionic,Gonadotropin, Human Chorionic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000022 Abortion, Spontaneous Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference. Abortion, Tubal,Early Pregnancy Loss,Miscarriage,Spontaneous Abortion,Abortions, Spontaneous,Abortions, Tubal,Early Pregnancy Losses,Loss, Early Pregnancy,Losses, Early Pregnancy,Miscarriages,Pregnancy Loss, Early,Pregnancy Losses, Early,Spontaneous Abortions,Tubal Abortion,Tubal Abortions
D001609 Beta-Globulins Serum proteins with an electrophoretic mobility that falls between ALPHA-GLOBULINS and GAMMA-GLOBULINS. Beta(1)CA Globulin,Beta-Globulin,Beta Globulin,Beta Globulins
D014327 Trophoblasts Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA). Cytotrophoblasts,Syncytiotrophoblasts,Trophoblast,Cytotrophoblast,Syncytiotrophoblast

Related Publications

V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
[Comparative evaluation of methods for determining trophoblastic beta-globulin].
January 1981, Laboratornoe delo,
V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
[Use of the immunodiffusion test for trophoblastic beta 1-globulin in abortion].
April 1979, Akusherstvo i ginekologiia,
V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
[Determination of trophoblastic beta i globulin by means of counter immunoelectrophoresis].
January 1979, Laboratornoe delo,
V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
[Changes in the level of serum trophoblastic beta 1-globulin in threatened abortion].
January 1995, Akusherstvo i ginekologiia,
V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
[Alpha fetoprotein, trophoblastic beta globulin and alpha 2G globulin levels in the mother-fetus system in prolonged pregnancy].
May 1983, Akusherstvo i ginekologiia,
V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
Serum immunoglobulin and beta 1C-beta 1A globulin concentrations in juvenile rheumatoid arthritis.
January 1974, Annals of the rheumatic diseases,
V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
[Trophoblastic immunoglobulin transport system].
March 1981, Akusherstvo i ginekologiia,
V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
[Evaluation of a trophoblastic beta-globulin preparation in the leukocyte adhesion inhibition test during pregnancy].
July 1981, Biulleten' eksperimental'noi biologii i meditsiny,
V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
[Simultaneous immunochemical determination of pregnancy proteins alpha 2-glycoprotein and trophoblastic beta 1-globulin].
January 1983, Laboratornoe delo,
V N Migunov, and I M Pozina, and L V Minakova, and P G Prokopenko, and Iu S Tatarinov
[Immunoglobulin preparations].
April 2012, Nihon rinsho. Japanese journal of clinical medicine,
Copied contents to your clipboard!