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Effects in vitro of glutamate, aspartate, fumarate and malate on substrate activation kinetics of AMP-deaminase in denervated and contralateral gastrocnemius muscles of the frog, Rana hexadactyla were studied. Glutamate increase the enzyme activity of both muscles by increasing maximal velocity (V) and decreasing Michaelis-Menten constant (Km), whereas, aspartate did not show any significant effect. Fumarate and malate exerted mixed type of inhibition by decreasing V and increasing Km of enzymes in both muscle preparations. The inhibitor constant (Ki) values suggest that the denervated muscle enzyme was more sensitive to fumarate and malate as compared to the contralateral muscle enzyme.
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
April 1974,
Bollettino della Societa italiana di biologia sperimentale,
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
January 1983,
No to hattatsu = Brain and development,
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
August 1980,
The Biochemical journal,
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
July 1981,
Biochemical and biophysical research communications,
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
January 1990,
The Biochemical journal,
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
January 1983,
Comparative biochemistry and physiology. B, Comparative biochemistry,
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
January 1986,
Ukrainskii biokhimicheskii zhurnal (1978),
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
January 1985,
The American journal of physiology,
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
July 1986,
Biulleten' eksperimental'noi biologii i meditsiny,
C Sreeramulu Chetty, and
R Chandramohan Naidu, and
K Sreenivasa Moorthy, and
K S Swami
June 1978,
Biochimica et biophysica acta,
