-transparent.png){kind=logo}
A combined morphologic and histochemical study of metaplastic polyps of the colorectum was undertaken. With increasing size, these lesions showed alterations in architecture and differentiation, increased secretion of carcinoembryonic antigen and a reduced secretion of O-acylated sialomucin. These functional changes are also observed in colorectal cancers, but not in tubular adenomas showing low-grade dysplasia. Since there is little clinical evidence for a metaplastic polyp-carcinoma sequence, it is suggested that the sets of factors which lead to adenoma and metaplastic polyp formation in the colorectum are both required to induce malignant transformation.
Related Publications
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
September 1980,
Histopathology,
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
March 1980,
Histopathology,
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
September 1984,
The American journal of surgical pathology,
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
March 2024,
Gastroenterology clinics of North America,
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
January 1966,
Rivista di patologia clinica e sperimentale,
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
January 1983,
Lancet (London, England),
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
June 1994,
The Histochemical journal,
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
December 2007,
Gastroenterology clinics of North America,
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
May 1989,
Minerva chirurgica,
J R Jass, and
M I Filipe, and
S Abbas, and
C A Falcon, and
Y Wilson, and
D Lovell
November 2001,
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc,
