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The nature and location of intermediate filament proteins (IFP) may provide new insights into the origin and differentiation of neoplastic cells. An immunofluorescent study of these IFP in a case of a granular cell ameloblastoma revealed that all tumor cells contained the IFP keratin. Some granular cells, however, also contained the IFP vimentin, which is considered specific for mesenchymal tissues only. The implications of these observations are discussed. Study with monoclonal antibodies indicated the origin of the ameloblastoma from non-keratinized squamous epithelium. A comparison of the anti-keratin immunofluorescence pattern of the ameloblast-like cells in the present tumor with ameloblasts in the tooth germ revealed no similarities, indicating that despite some resemblance of the peripheral columnar cells to ameloblasts, these cells differ in other aspects.
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
June 1996,
Pathology, research and practice,
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
January 2017,
Journal of oral and maxillofacial pathology : JOMFP,
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
August 1974,
Oral surgery, oral medicine, and oral pathology,
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
January 2002,
Acta histochemica,
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
January 2012,
Journal of oral and maxillofacial pathology : JOMFP,
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
September 2010,
Journal of maxillofacial and oral surgery,
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
July 2014,
Journal of pharmacy & bioallied sciences,
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
April 1987,
Pathology, research and practice,
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
May 1988,
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques,
P C de Wilde, and
P J Slootweg, and
H Müller, and
A Kant, and
O Moesker, and
P Vooijs, and
F C Ramaekers
June 1989,
International journal of oral and maxillofacial surgery,
