Synovial sarcoma: an Australian series of 48 cases. 1984

R A Zito

A series of 48 cases of synovial sarcomas submitted to the Australasian Soft Tissue Tumour Registry between 1965 and 1980 is reported. Tumours were analysed with regard to clinical features, morphology and outcome. The overall 5-yr survival rate for all assessable cases was 50%. A strong relationship between size and survival was noted with a 73% 5-yr survival rate where tumours were less than 5 cm in maximum diameter. Biphasic tumours (16 cases) appeared to have a better prognosis, with a mean survival time of 6.1 yr as compared with 4 yr for monophasic tumours (32 cases); however, the former were generally slightly smaller tumours. Tumours with less than 5 mitoses per 10 highpower fields (2.8 sq mm) had double the mean survival time of other tumours. The histological features of swirling architecture, monotonous cell type, vascular pattern, myxoid foci, collagen production, mast cell presence and calcification are recommended as cumulative factors in arriving at a diagnosis where a biphasic pattern is not apparent.

UI MeSH Term Description Entries
D008297 Male Males
D008407 Mast Cells Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR. Basophils, Tissue,Basophil, Tissue,Cell, Mast,Cells, Mast,Mast Cell,Tissue Basophil,Tissue Basophils
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002114 Calcinosis Pathologic deposition of calcium salts in tissues. Calcification, Pathologic,Calcinosis, Tumoral,Microcalcification,Microcalcinosis,Pathologic Calcification,Calcinoses,Calcinoses, Tumoral,Microcalcifications,Microcalcinoses,Tumoral Calcinoses,Tumoral Calcinosis
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D003094 Collagen A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH). Avicon,Avitene,Collagen Felt,Collagen Fleece,Collagenfleece,Collastat,Dermodress,Microfibril Collagen Hemostat,Pangen,Zyderm,alpha-Collagen,Collagen Hemostat, Microfibril,alpha Collagen
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005121 Extremities The farthest or outermost projections of the body, such as the HAND and FOOT. Limbs,Extremity,Limb
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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