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The immediate heart-rate response to standing was measured in 22 normal controls and 25 patients with diabetes, 15 of whom had autonomic neuropathy. The response in the controls and patients without autonomic neuropathy was characteristic and consistent, with tachycardia maximal at around the 15th beat and relative bradycardia maximal at around the 30th beat. The diabetics with autonomic neuropathy, however, showed a flat response. In three controls the response was abolished with intravenous atropine but not with propranolol, showing that it is mediated through the vagus. A simplified test using routine ECGs and measuring the R-R interval at beats 15 and 30 with a ruler is easily performed as an outpatient procedure and may be used as a measure of autonomic function in diabetes.
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
September 1983,
Australian paediatric journal,
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
February 1978,
British medical journal,
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
May 1978,
British medical journal,
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
January 1987,
Diabetic medicine : a journal of the British Diabetic Association,
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
January 1985,
Clinical physiology (Oxford, England),
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
September 1983,
British medical journal (Clinical research ed.),
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
January 1984,
Indian heart journal,
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
January 1982,
Clinical science (London, England : 1979),
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
January 1979,
Acta medica Scandinavica,
D J Ewing, and
I W Campbell, and
A Murray, and
J M Neilson, and
B F Clarke
November 1982,
Rinsho byori. The Japanese journal of clinical pathology,
