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We have developed a series of monoclonal antibodies against the calf strain RIT 4237 (subgroup 1) and the human strain 82-561 (subgroup 3) of rotavirus, both grown in tissue culture, and also against the human rotavirus 81-2162 (subgroup 2), extracted from a fecal specimen. A variety of different specificities was observed among these antibodies, namely, antibodies against group and subgroup determinants, as well as neutralizing antibodies. By using monoclonal antibodies against the subgroup antigen in an enzyme-linked immunoassay system, the constant predominance of subgroup 2 viruses in humans was confirmed in 74 stools collected from children in Brussels who suffered a diarrheal illness between July 1981 and June 1983. The availability of these antibodies also made it possible to improve the sensitivity and the specificity of the test system.
J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
September 1989,
Blood,
J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
February 1994,
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J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
June 1971,
European journal of immunology,
J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
February 2014,
Monoclonal antibodies in immunodiagnosis and immunotherapy,
J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
June 1987,
Hybridoma,
J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
January 1988,
Immunology and cell biology,
J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
January 1988,
Archives of virology,
J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
September 1980,
FEBS letters,
J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
October 1988,
BioTechniques,
J P Lambert, and
P Marbehant, and
D Marissens, and
G Zissis
October 1984,
Journal of clinical microbiology,
