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In 15 pigmented rabbits a pars plana lensectomy, vitrectomy and giant retinal tear with bullous retinal detachment were produced with maintenance of an intact anterior lens capsule. The incidence of subsequent rubeosis iridis, as detected angiographically, was compared with that in a control group of animals in whom the anterior lens capsule was not preserved but whose management was identical in all other respects. The rubeosis in the rabbits was angiographically identical to that seen in humans following vitrectomy, with immediate formation of a mossy hyperfluorescent surface membrane that leaked fluorescein extensively into the anterior chamber in the late phase of the angiography. It was possible to distinguish true neovascularization from breakdown of the blood-ocular barrier by the time and extent of the fluorescein leakage. Preservation of an intact anterior lens capsule reduced the incidence of unequivocal (florid) rubeosis from 73% to 33% (p less than 0.05).
K Moffat, and
M S Blumenkranz, and
E Hernandez
December 1946,
American journal of ophthalmology,
K Moffat, and
M S Blumenkranz, and
E Hernandez
January 1951,
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina,
K Moffat, and
M S Blumenkranz, and
E Hernandez
January 1970,
Acta medica Academiae Scientiarum Hungaricae,
K Moffat, and
M S Blumenkranz, and
E Hernandez
July 1971,
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie,
K Moffat, and
M S Blumenkranz, and
E Hernandez
January 1949,
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde,
K Moffat, and
M S Blumenkranz, and
E Hernandez
March 1967,
American journal of ophthalmology,
K Moffat, and
M S Blumenkranz, and
E Hernandez
January 2017,
The Pan African medical journal,
K Moffat, and
M S Blumenkranz, and
E Hernandez
February 1947,
American journal of ophthalmology,
K Moffat, and
M S Blumenkranz, and
E Hernandez
June 1966,
Annales d'oculistique,
