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The T cell hybridoma (#5104-2) which produces a suppressor factor to suppress the hen egg-white lysozyme (HEL) specific T cell proliferative response in an antigen specific manner was developed in our laboratories. Suppression by this suppressor factor require an I-J subregion matching between suppressor factor donor and donor of HEL-specific proliferative T cells. The Igh restriction between this suppressor factor donor and HEL-primed responder cell donor has not yet been observed in our experimental system. This suppressor factor has binding activity to HEL and is bound to anti-I-J antibody columns. It was also found to suppress the HEL specific delayed type hypersensitivity (DTH) responses when administered at the induction phase.
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November 1984,
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology,
T Nagatani, and
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Journal of immunology (Baltimore, Md. : 1950),
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Immunology letters,
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March 1985,
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology,
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Y Aihara, and
K Matsunaga, and
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M Minami, and
K Okuda
September 1994,
The Journal of experimental medicine,
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September 1993,
Journal of immunology (Baltimore, Md. : 1950),
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January 1981,
Microbiology and immunology,
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May 1998,
Journal of biochemistry,
