-transparent.png){kind=logo}
The effect of a low protein-calorie diet (restricted diet) on cellular growth and on RNA metabolism in Wistar rat liver has been studied. Experimentation was carried out over 30 days and the comparisons were made against well-nourished group (10% protein, controls). Liver weight and hepatic proteins dropped significantly in malnourished rats. Both rate of DNA and number of nuclei were unchanged. However, protein/DNA and liver weight/number of nuclei ratios decreased, which led to an atrophy phenomenon. DNase specific activity however, was not modified. Liver RNA content together with RNase activity dropped in deficient rats. Protein synthesis capacity (RNA/protein) did not change. These results suggest that restricted diet leads to a lower hepatocyte size with a decreased rat of RNA turnover.
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
June 1979,
American heart journal,
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
April 1987,
The Tohoku journal of experimental medicine,
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
August 1969,
Nutrition reviews,
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
January 1972,
Progress in liver diseases,
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
March 1969,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
June 1992,
The Clinical investigator,
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
January 1968,
Vitamins and hormones,
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
November 1976,
Indian pediatrics,
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
April 1979,
Revista da Escola de Enfermagem da U S P,
A Marcos, and
E Muñoz-Martínez, and
M T Unzaga, and
J L Rey de Viñas, and
G Varela
April 1978,
The American journal of clinical nutrition,
