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Ventricular vulnerability may be assessed by measuring the threshold current for the induction of ventricular fibrillation (VF). This technique has been widely utilized in animal experimentation and has been safely applied in a small number of clinical studies. We measured the VF threshold (VFT), using the single stimulus technique in 10 patients with coronary artery disease just prior to the institution of cardiopulmonary bypass. There were no adverse effects of VFT measurement. Three patients had nonsustained ventricular tachycardia (VT) on 24-hour ambulatory monitoring and had VFTs of 10, 14, and 16 mA. In this group VF was induced without any preceding repetitive ventricular responses. Seven patients had no repetitive forms on ambulatory monitoring. Their VFTs ranged from 30 to greater than 40 mA (mean greater than 37). Repetitive extrasystoles were regularly observed in this group at current intensities which ranged from 53% to 80% of the VFT. Thus patients with manifest VT appear to have an enhanced vulnerability to VF. Single or multiple responses were not observed in these patients but appeared to be present in patients with coronary disease and no demonstrable rhythm disorder.
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
March 1998,
Chaos (Woodbury, N.Y.),
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
February 1985,
Vnitrni lekarstvi,
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
November 1997,
Journal of the American College of Cardiology,
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
January 1998,
The American journal of cardiology,
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
November 2000,
Current cardiology reports,
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
January 1964,
Zeitschrift fur Psycho-somatische Medizin,
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
July 2002,
Nihon rinsho. Japanese journal of clinical medicine,
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
May 1983,
Pacing and clinical electrophysiology : PACE,
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
July 2009,
Expert review of cardiovascular therapy,
P R Kowey, and
S Khuri, and
M Josa, and
R L Verrier, and
S Sharma, and
J P Kiely, and
E D Folland, and
A F Parisi
September 1987,
The American journal of medicine,
