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IgE-mediated histamine release from whole blood was analyzed in 44 patients with bronchial asthma by observing maximum present release and dose-response curves of histamine release induced by anti-IgE and house dust extract. The maximum histamine release from whole blood induced by anti-IgE correlated with total serum IgE levels. There was a close correlation between allergen-induced release from whole blood and the serum levels of specific IgE antibodies. In the maximum histamine release from whole blood induced by both anti-IgE and allergen, the interaction with a serum factor was not clearly recognized. Effect of a serum factor was shown in the dose-response curves of anti-IgE-induced histamine release, but not in those of allergen-induced histamine release. The dose-response curves caused by anti-IgE showed that basophils from cases with a high serum IgE level require much more anti-IgE to produce maximum histamine release than basophils from cases with a low serum IgE level. The results showed that IgE molecules contained in the serum participate in anti-IgE-induced histamine release from whole blood.
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
April 1980,
Agents and actions,
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
January 1980,
International archives of allergy and applied immunology,
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
June 1988,
Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine,
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
October 1969,
Journal of immunology (Baltimore, Md. : 1950),
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
April 1983,
Journal of immunology (Baltimore, Md. : 1950),
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
January 1973,
International archives of allergy and applied immunology,
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
January 1977,
International archives of allergy and applied immunology,
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
October 1979,
Journal of immunology (Baltimore, Md. : 1950),
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
October 1969,
Journal of immunology (Baltimore, Md. : 1950),
Y Tanizaki, and
H Komagoe, and
M Sudo, and
H Morinaga, and
S Nakagawa, and
H Kitani, and
K Takahashi, and
I Kimura
January 1987,
Microbiology and immunology,
