BIOMAT Database Logo BIOMAT Database Logo

Alzheimer's disease and Down's syndrome. 1982

D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009474 Neurons The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM. Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D009929 Organ Size The measurement of an organ in volume, mass, or heaviness. Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002794 Choline A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. Bursine,Fagine,Vidine,2-Hydroxy-N,N,N-trimethylethanaminium,Choline Bitartrate,Choline Chloride,Choline Citrate,Choline Hydroxide,Choline O-Sulfate,Bitartrate, Choline,Chloride, Choline,Choline O Sulfate,Citrate, Choline,Hydroxide, Choline,O-Sulfate, Choline
D002795 Choline O-Acetyltransferase An enzyme that catalyzes the formation of acetylcholine from acetyl-CoA and choline. EC 2.3.1.6. Choline Acetylase,Choline Acetyltransferase,Acetylase, Choline,Acetyltransferase, Choline,Choline O Acetyltransferase,O-Acetyltransferase, Choline
D003704 Dementia An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness. Senile Paranoid Dementia,Amentia,Familial Dementia,Amentias,Dementia, Familial,Dementias,Dementias, Familial,Dementias, Senile Paranoid,Familial Dementias,Paranoid Dementia, Senile,Paranoid Dementias, Senile,Senile Paranoid Dementias
D004314 Down Syndrome A chromosome disorder associated either with an extra CHROMOSOME 21 or an effective TRISOMY for chromosome 21. Clinical manifestations include HYPOTONIA, short stature, BRACHYCEPHALY, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, single transverse palmar crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213) Mongolism,Trisomy 21,47,XX,+21,47,XY,+21,Down Syndrome, Partial Trisomy 21,Down's Syndrome,Partial Trisomy 21 Down Syndrome,Trisomy 21, Meiotic Nondisjunction,Trisomy 21, Mitotic Nondisjunction,Trisomy G,Downs Syndrome,Syndrome, Down,Syndrome, Down's
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Alzheimer's Disease and Down's Syndrome.
March 1988, The Western journal of medicine,
D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Down's syndrome and Alzheimer's disease.
August 1984, Annals of neurology,
D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Down's syndrome and Alzheimer's disease.
October 1993, Journal (Canadian Dental Association),
D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Alzheimer's disease and Down's syndrome.
August 1988, Histopathology,
D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Alzheimer's disease in Down's syndrome.
March 1971, American journal of mental deficiency,
D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Down's syndrome, longevity, and Alzheimer's disease.
February 1993, The British journal of psychiatry : the journal of mental science,
D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Atherosclerosis, Down's syndrome, and Alzheimer's disease.
September 1977, British medical journal,
D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Alzheimer's disease, Down's syndrome, and aging.
January 1982, Annals of the New York Academy of Sciences,
D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Down's syndrome, longevity, and Alzheimer's disease.
May 1993, The British journal of psychiatry : the journal of mental science,
D L Price, and P J Whitehouse, and R G Struble, and J T Coyle, and A W Clark, and M R Delong, and L C Cork, and J C Hedreen
Genetics of Down's syndrome and Alzheimer's disease.
August 2002, The British journal of psychiatry : the journal of mental science,
Copied contents to your clipboard!