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Whole body autoradiograms of male, spayed and pregnant female mice after injection of [3H]zearalenone showed a rapid excretion of radioactivity into the bile as well as the urine. Specific localization was found in oestrogen target organs as the uterus, interstitial cells of the testicle and the follicles of the ovary. Unlike natural oestrogens zearalenone and/or its metabolites were not found in the adrenal cortex and bronchi of the lungs. Detection of radioactivity in an increased amount of fluid in the pleural and peritoneal cavities suggests an additional site of action of zearalenone. In the pregnant mice used, radioactivity was found only in the foetuses of late pregnancy mainly in the kidney, bile and connective tissue.
L E Appelgren, and
R G Arora, and
P Larsson
January 1971,
Strahlentherapie,
L E Appelgren, and
R G Arora, and
P Larsson
January 1978,
Cellular and molecular biology, including cyto-enzymology,
L E Appelgren, and
R G Arora, and
P Larsson
January 1980,
Hormone research,
L E Appelgren, and
R G Arora, and
P Larsson
September 1973,
Indian journal of cancer,
L E Appelgren, and
R G Arora, and
P Larsson
July 1984,
Experimental eye research,
L E Appelgren, and
R G Arora, and
P Larsson
October 1965,
Biochimica et biophysica acta,
L E Appelgren, and
R G Arora, and
P Larsson
June 1967,
Biken journal,
L E Appelgren, and
R G Arora, and
P Larsson
November 1978,
Acta pharmacologica et toxicologica,
L E Appelgren, and
R G Arora, and
P Larsson
October 1967,
European journal of pharmacology,
L E Appelgren, and
R G Arora, and
P Larsson
January 1974,
Experimentelle Pathologie,
