-transparent.png){kind=logo}
20 patients with distal onychomycosis were given daily application of an ointment containing 2% tolnaftate and an ointment containing 20% urea under ODT. Following this, 17 of 20 patients developed onychomalacia and seven of these developed onycholysis 1 or 2 weeks later. The separated nails were cut as short as possible. Similarly to those patients with onychomalacia alone, occlusive dressing technique was continuously performed until the newly developed nails became macroscopically normal and no fungi were observed microscopically (responders). Following treatment, out of 20 patients, 14 responded. 5 patients who had a short course of treatment did not respond. Side-effects such as pain, hemorrhage and infection did not occur.
M Ishii, and
T Hamada, and
Y Asai
January 1992,
Dermatology (Basel, Switzerland),
M Ishii, and
T Hamada, and
Y Asai
January 2000,
Pediatric dermatology,
M Ishii, and
T Hamada, and
Y Asai
October 1998,
The Journal of dermatology,
M Ishii, and
T Hamada, and
Y Asai
April 1990,
Mycoses,
M Ishii, and
T Hamada, and
Y Asai
February 1992,
Harefuah,
M Ishii, and
T Hamada, and
Y Asai
July 2014,
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete,
M Ishii, and
T Hamada, and
Y Asai
January 1948,
Therapie der Gegenwart,
M Ishii, and
T Hamada, and
Y Asai
January 1997,
International journal of dermatology,
M Ishii, and
T Hamada, and
Y Asai
November 1999,
Journal of the European Academy of Dermatology and Venereology : JEADV,
M Ishii, and
T Hamada, and
Y Asai
January 1991,
Mycoses,
