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The myocardium of Wistar rats was studied by electron microscopy after ligation of the renal artery resulting in a stable elevation of blood pressure. The ultrastructural data on the development of heart hypertrophy were described within 5 to 35 days after operation using the morphometric and stereological methods and correlation analysis. The hypertrophied cardiomyocytes showed a reduction in the ratio of the total volume density of the mitochondria, sarcoplasmic reticulum and T system to the volume density of myofibrils. It was discovered that hypertrophy of cardiomyocytes is marked by an increase in the sarcoplasmic reticulum rather than in myofibrils and other cell compartments, whereas the relative volume of mitochondria decreases.
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
March 1979,
Cardiovascular research,
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
October 1983,
Biulleten' eksperimental'noi biologii i meditsiny,
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
January 1971,
Arkhiv patologii,
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
May 2005,
Annals of the New York Academy of Sciences,
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
January 1996,
Folia morphologica,
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
February 1997,
Biulleten' eksperimental'noi biologii i meditsiny,
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
January 1997,
Heart and vessels,
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
June 1984,
Biulleten' eksperimental'noi biologii i meditsiny,
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
January 1973,
Vrachebnoe delo,
E L Lushnikova, and
L M Nepomniashchikh, and
V P Tumanov, and
G I Nepomniashchikh, and
A M Gonchar
January 1989,
Gegenbaurs morphologisches Jahrbuch,
