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This study has been performed to evaluate the in vivo effect of acetylsalicylic acid (ASA) i.v. infusion at two different dosages: 500 and 2,000 mg on the main hemorheological parameters (blood viscosity and filtrability, hematocrit) and on beta-thromboglobulin (a platelet-specific protein) in patients with peripheral obliterative arterial disease, before and after an ischemic exercise. The results obtained before and 3 and 24 h after the drug administration induced us to think that platelet-specific substances released during the ischemic exercise can affect the hemorheological parameters and that ASA may be able to interfere with these reactions by inhibiting the platelet release.
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
January 1983,
La Ricerca in clinica e in laboratorio,
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
November 1977,
American journal of clinical pathology,
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
January 1983,
La Ricerca in clinica e in laboratorio,
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
February 1977,
Acta hepato-gastroenterologica,
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
April 1977,
Minerva ginecologica,
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
June 1986,
Kardiologiia,
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
November 1986,
Experimental and clinical endocrinology,
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
May 2008,
Neurological research,
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
January 1985,
Experimental brain research,
A Vittoria, and
M Guerrini, and
D Pieragalli, and
C Del Bigo, and
G Martelli, and
M Franchi, and
G Messa, and
P Blardi, and
C Galigani, and
T Di Perri
July 1980,
Journal of clinical pharmacology,
