-transparent.png){kind=logo}
The photosensitizing/cytotoxic effects of four porphyrin compounds derived from hematoporphyrin were compared using two human tumor cell lines with a soft-agar colony-forming assay. Reproducible dose- and time-dependent increases in reproductive cell death were observed for each porphyrin tested. Two fractions derived from hematoporphyrin derivative (HPD) were found to be better photosensitizers than HPD itself, indicating the potential value of this in vitro assay for detecting the most active component from a heterogeneous mixture.
Related Publications
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
February 1982,
Cancer letters,
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
January 1987,
Photochemistry and photobiology,
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
February 1984,
Cancer research,
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
October 2014,
Journal of visualized experiments : JoVE,
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
January 1989,
Anticancer research,
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
August 2016,
Cold Spring Harbor protocols,
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
August 1985,
Gan to kagaku ryoho. Cancer & chemotherapy,
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
February 1992,
Journal of photochemistry and photobiology. B, Biology,
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
December 1983,
The Journal of investigative dermatology,
C A Jones, and
C B Uhl, and
V R Mattox, and
J H Kinsey, and
D A Cortese, and
M M Lieber
June 2017,
Bio-protocol,
